Keratitis Ichthyosis Deafness (KID) Syndrome is a rare genetic disorder that affects the skin, eyes, and ears. It is characterized by three main symptoms: keratitis (inflammation of the cornea), ichthyosis (a skin condition causing dry, scaly skin), and deafness.
Individuals with KID Syndrome often experience vision problems due to corneal inflammation, which can lead to vision loss if left untreated. The skin abnormalities associated with ichthyosis can vary in severity, ranging from mild dryness to thickened, scaly patches. Additionally, hearing loss is a common feature of this syndrome, which can be present from birth or develop over time.
KID Syndrome is caused by mutations in a specific gene that plays a role in the development and maintenance of the skin, eyes, and ears. It is typically inherited in an autosomal dominant pattern, meaning an affected individual has a 50% chance of passing the condition on to their children.
Management of KID Syndrome involves a multidisciplinary approach, including regular eye examinations, skincare routines to manage ichthyosis, and hearing aids or cochlear implants for hearing loss. Genetic counseling is also recommended for affected individuals and their families.