What is the prevalence of Klippel-Trénaunay-Weber Syndrome?
How many people does Klippel-Trénaunay-Weber Syndrome affect? Does it have the same prevalence in men and women? And in the different countries?
Klippel-Trénaunay-Weber Syndrome is a rare congenital disorder characterized by a triad of symptoms: port-wine stain birthmark, varicose veins, and abnormal growth of bones and soft tissues. The prevalence of this syndrome is estimated to be around 1 in 100,000 to 1 in 1,000,000 individuals. It affects both males and females equally, with no specific ethnic or geographic predisposition. Although it is a rare condition, it can significantly impact the quality of life for those affected, requiring multidisciplinary medical management and support.
Klippel-Trénaunay-Weber Syndrome (KTWS) is a rare congenital disorder characterized by a triad of symptoms: port-wine stain birthmarks, varicose veins, and soft tissue and bone overgrowth. The prevalence of KTWS is estimated to be around 1 in 100,000 individuals, making it a relatively uncommon condition.
KTWS affects both males and females equally and can manifest at birth or become apparent during infancy or early childhood. The port-wine stain birthmarks are typically present at birth and can vary in size and location. These birthmarks are caused by abnormal blood vessels near the surface of the skin.
Varicose veins are another characteristic feature of KTWS, appearing as enlarged, twisted veins that may cause discomfort or pain. The severity of varicose veins can vary among individuals with KTWS.
In addition to the visible symptoms, KTWS can also involve soft tissue and bone overgrowth. This overgrowth can affect one or more limbs and may lead to differences in limb length or girth.
While KTWS is a lifelong condition, management primarily focuses on addressing the symptoms and associated complications. Treatment options may include laser therapy for birthmarks, compression stockings for varicose veins, and surgical interventions for overgrowth-related issues.
