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Lennox-Gastaut syndrome synonyms

What other names are the Lennox-Gastaut syndrome known by? Synonyms and other terms with which Lennox-Gastaut syndrome is known.

Lennox-Gastaut syndrome is also known as...


Lennox-Gastaut syndrome (LGS) is a rare and severe form of epilepsy that typically begins in childhood. It is characterized by multiple types of seizures, cognitive impairment, and abnormal electrical activity in the brain. LGS is often resistant to treatment, making it challenging to manage and control.



Synonyms for Lennox-Gastaut syndrome include:



  • Lennox syndrome

  • Gastaut syndrome

  • Lennox-Gastaut disease

  • Severe childhood epileptic encephalopathy



The hallmark of Lennox-Gastaut syndrome is the presence of multiple seizure types, including tonic seizures (characterized by stiffening of the muscles), atonic seizures (resulting in sudden loss of muscle tone), and atypical absence seizures (brief loss of awareness). These seizures can be frequent and difficult to control, leading to a significant impact on the individual's quality of life.



In addition to seizures, individuals with LGS often experience cognitive impairment, behavioral problems, and developmental delays. The cognitive difficulties can range from mild to severe, affecting learning, memory, and overall intellectual functioning. Behavioral issues may include hyperactivity, aggression, and social difficulties.



The exact cause of Lennox-Gastaut syndrome is often unknown, but it can be associated with various underlying conditions, such as brain malformations, genetic mutations, or brain injuries. Diagnosis of LGS involves a comprehensive evaluation, including medical history, neurological examination, and electroencephalogram (EEG) to detect abnormal brain wave patterns.



Treatment for Lennox-Gastaut syndrome typically involves a combination of antiepileptic medications, such as valproic acid, lamotrigine, or topiramate. However, these medications may only provide partial seizure control, and other treatment options, including ketogenic diet, vagus nerve stimulation, or epilepsy surgery, may be considered in severe cases.



In conclusion, Lennox-Gastaut syndrome, also known as Lennox syndrome or Gastaut syndrome, is a rare and severe form of epilepsy characterized by multiple seizure types, cognitive impairment, and abnormal brain activity. It poses significant challenges in management and treatment, requiring a multidisciplinary approach to address the complex needs of individuals living with LGS.


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My daughter Katie was born perfectly healthy and "normal". When she was 8 months old, she got sick and had her first seizure. Her first three seizures were within 13 hours and each lasted longer than a half hour. Almost 4 years later, we are still ba...
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LGS may usually be diagnosed at a younger age like 3-5, but my daughter was 10 and in 4th grade when she started having seizures. Her neurologist at DHMC was surprised when she was coming out of status epilepticus, after a couple days of IV therapy a...

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