Limb-girdle muscular dystrophy (LGMD) is a group of genetic disorders that primarily affect the muscles around the hips and shoulders. There are several subtypes of LGMD, each caused by different gene mutations. Symptoms and age of onset can vary widely depending on the specific subtype.
If you are concerned that you may have LGMD, it is important to consult with a healthcare professional for a proper diagnosis. Here are some signs and symptoms commonly associated with LGMD:
Muscle weakness: LGMD typically presents with progressive muscle weakness, particularly in the hip and shoulder muscles. This weakness may affect your ability to walk, climb stairs, lift objects, or raise your arms overhead.
Difficulty with mobility: As LGMD progresses, you may experience difficulty with mobility and balance. You may notice a waddling gait, frequent falls, or trouble getting up from a seated or lying position.
Proximal muscle involvement: LGMD primarily affects the proximal muscles, which are the muscles closest to the center of your body. This includes the muscles of the upper arms, shoulders, thighs, and hips.
Muscle wasting: Over time, LGMD can lead to muscle wasting or atrophy. This may result in visible changes in muscle size and shape.
Contractures: Some individuals with LGMD may develop joint contractures, which are permanent tightening of the muscles and tendons around a joint. This can limit your range of motion and flexibility.
Family history: LGMD is typically inherited in an autosomal recessive or autosomal dominant manner. If you have a family history of LGMD or other neuromuscular disorders, it may increase your risk of having the condition.
Diagnostic tests: To confirm a diagnosis of LGMD, your healthcare provider may perform various tests, including genetic testing, muscle biopsy, electromyography (EMG), and imaging studies. These tests help identify the specific subtype of LGMD and rule out other possible causes of muscle weakness.
If you are experiencing any of these symptoms or have concerns about LGMD, it is crucial to seek medical evaluation. Remember, only a healthcare professional can provide an accurate diagnosis and guide you towards appropriate management and support.