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Which are the symptoms of Locked In Syndrome?

See the worst symptoms of affected by Locked In Syndrome here

Locked In Syndrome symptoms

Symptoms of Locked-In Syndrome


Locked-In Syndrome (LIS) is a rare neurological condition characterized by complete paralysis of nearly all voluntary muscles in the body, except for the muscles controlling eye movement. Individuals with Locked-In Syndrome are often unable to speak or move their limbs, resulting in a profound loss of motor function. This condition is typically caused by damage to the brainstem, which is responsible for transmitting signals between the brain and the rest of the body.



1. Paralysis: The hallmark symptom of Locked-In Syndrome is paralysis. Individuals with LIS experience a complete loss of voluntary muscle control, including the inability to move their arms, legs, or facial muscles. However, they can still retain some control over their eye movements, which becomes their primary means of communication.



2. Loss of speech: Locked-In Syndrome often leads to the loss of speech due to the paralysis of the muscles involved in vocalization. While individuals with LIS may be fully conscious and cognitively intact, they are unable to produce any audible speech. However, they can still communicate through alternative methods, such as eye movements, blinking, or using assistive communication devices.



3. Eye movement abnormalities: Despite the paralysis affecting most of their body, individuals with Locked-In Syndrome can typically move their eyes freely. Eye movements become crucial for communication, as they can use specific eye movements to answer yes or no questions, spell out words, or select options on a communication board.



4. Preserved cognitive function: While LIS severely limits physical abilities, it does not affect cognitive function. Individuals with Locked-In Syndrome remain fully aware, alert, and mentally capable. They can understand and process information, experience emotions, and maintain their intellectual abilities. This preserved cognitive function often leads to frustration and a desire to communicate their thoughts and feelings.



5. Sensory intactness: Despite the paralysis, individuals with Locked-In Syndrome typically retain intact sensory function. They can see, hear, taste, and feel sensations just like individuals without LIS. This sensory intactness is essential for their ability to interact with the world and receive information from their surroundings.



6. Emotional changes: Locked-In Syndrome can lead to emotional changes and psychological distress. The frustration and isolation resulting from the inability to communicate and move freely can cause feelings of depression, anxiety, and a sense of being trapped within one's own body. Support from healthcare professionals, family, and friends is crucial in addressing these emotional challenges.



7. Dependence on assistive devices: Individuals with Locked-In Syndrome often require assistive devices and technologies to communicate and perform daily activities. Eye-tracking devices, communication boards, and computer-based assistive technologies can help them express their thoughts, needs, and desires. These devices enable individuals with LIS to regain some level of independence and maintain social connections.



Locked-In Syndrome is a devastating condition that profoundly affects the lives of those who experience it. While the physical limitations are significant, it is important to recognize that individuals with LIS retain their cognitive abilities and desire for communication. Providing support, understanding, and access to assistive technologies can greatly improve their quality of life and help them overcome the challenges associated with Locked-In Syndrome.


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