Lymphocytic infiltrate of Jessner, also known as Jessner lymphocytic infiltrate or Jessner-Kanof syndrome, is a rare chronic skin disorder characterized by the presence of infiltrating lymphocytes in the skin. It typically affects middle-aged adults and presents as multiple small, red to purple papules or plaques on the face, neck, and upper trunk.
Diagnosing lymphocytic infiltrate of Jessner requires a combination of clinical evaluation, histopathological examination, and exclusion of other similar conditions. The diagnosis is primarily made based on the characteristic clinical presentation and the histopathological findings.
Clinical evaluation: A dermatologist or a healthcare professional will assess the patient's medical history and perform a physical examination. They will look for the presence of multiple small, red to purple papules or plaques on the affected areas, such as the face, neck, or upper trunk. The clinical evaluation helps to differentiate lymphocytic infiltrate of Jessner from other skin conditions with similar presentations.
Histopathological examination: A skin biopsy is usually performed to confirm the diagnosis. During the procedure, a small piece of affected skin is removed and sent to a laboratory for microscopic examination. The histopathological examination reveals a dense infiltrate of lymphocytes in the upper dermis. The lymphocytes are typically arranged in a band-like pattern and may extend into the deeper layers of the skin. The presence of lymphoid follicles and plasma cells may also be observed.
Exclusion of other conditions: It is important to rule out other skin disorders that may have similar clinical or histopathological features. Conditions such as lupus erythematosus, cutaneous lymphoma, and other lymphocytic infiltrates need to be considered and excluded through additional tests or consultations with specialists.
In summary, the diagnosis of lymphocytic infiltrate of Jessner is based on the characteristic clinical presentation, histopathological examination, and exclusion of other similar conditions. A dermatologist or healthcare professional will evaluate the patient's medical history, perform a physical examination, and may recommend a skin biopsy to confirm the diagnosis.