Lymphocytic Infiltrate of Jessner, also known as Jessner's lymphocytic infiltrate or Jessner-Kanof syndrome, is a rare chronic skin condition characterized by the presence of infiltrating lymphocytes in the skin. It was first described by Dr. Edmund Jessner in 1953.
The exact cause of Lymphocytic Infiltrate of Jessner is unknown, but it is believed to be an autoimmune disorder. The condition primarily affects middle-aged adults, with women being more commonly affected than men. It typically presents as multiple, small, red or pink papules or plaques on the face, neck, or upper trunk.
Diagnosis of Lymphocytic Infiltrate of Jessner is made through a combination of clinical examination and skin biopsy. The skin biopsy reveals a dense infiltrate of lymphocytes in the upper dermis, with a characteristic absence of atypical cells.
Treatment for Lymphocytic Infiltrate of Jessner aims to control symptoms and prevent complications. Topical corticosteroids are commonly used as a first-line treatment, with more potent formulations reserved for resistant cases. Other treatment options include topical calcineurin inhibitors, systemic corticosteroids, and immunosuppressive agents.
Prognosis for Lymphocytic Infiltrate of Jessner is generally good, with most cases showing a chronic but benign course. However, relapses and remissions are common, and long-term follow-up is often necessary. In rare cases, Lymphocytic Infiltrate of Jessner may be associated with other autoimmune disorders, such as lupus erythematosus or Sjögren's syndrome.
In conclusion, Lymphocytic Infiltrate of Jessner is a rare chronic skin condition characterized by infiltrating lymphocytes in the skin. It primarily affects middle-aged adults and presents as red or pink papules or plaques. Diagnosis is made through clinical examination and skin biopsy. Treatment options include topical corticosteroids, calcineurin inhibitors, and systemic immunosuppressive agents. Prognosis is generally good, but long-term follow-up may be necessary.