Lymphocytic Infiltrate of Jessner, also known as Jessner's lymphocytic infiltrate, is a rare chronic skin condition characterized by the presence of infiltrating lymphocytes in the skin. It typically presents as small, red, raised lesions on the face, neck, or upper trunk. While the exact cause of this condition is unknown, it is believed to be an autoimmune disorder.
There is no specific cure for Lymphocytic Infiltrate of Jessner, but there are several treatment options available to manage the symptoms and reduce the severity of the condition. The choice of treatment depends on the individual's symptoms, the extent of the lesions, and the patient's overall health.
Topical steroids are commonly prescribed as a first-line treatment for Lymphocytic Infiltrate of Jessner. These medications help reduce inflammation, itching, and redness associated with the condition. They are available in various strengths and formulations, such as creams, ointments, or gels. It is important to follow the prescribed dosage and duration to avoid potential side effects of long-term steroid use.
Topical calcineurin inhibitors are another option for treating Lymphocytic Infiltrate of Jessner. These medications work by suppressing the immune response in the skin. They are particularly useful for sensitive areas, such as the face, where long-term steroid use may be undesirable. Tacrolimus and pimecrolimus are commonly prescribed calcineurin inhibitors for this condition.
In more severe cases or when topical treatments are ineffective, systemic steroids may be prescribed. These medications are taken orally or by injection and have a broader anti-inflammatory effect throughout the body. However, systemic steroids carry a higher risk of side effects, such as weight gain, mood changes, and increased susceptibility to infections. Therefore, they are typically used for short periods and under close medical supervision.
If topical or systemic steroids are not effective or well-tolerated, other immunosuppressive medications may be considered. These medications work by suppressing the immune system and reducing the inflammatory response. Examples include methotrexate, azathioprine, mycophenolate mofetil, and cyclosporine. These medications require regular monitoring of blood counts and liver function.
Phototherapy involves exposing the affected skin to specific wavelengths of ultraviolet light. This treatment can help reduce inflammation and slow down the immune response. Narrowband ultraviolet B (NB-UVB) and psoralen plus ultraviolet A (PUVA) are commonly used phototherapy options for Lymphocytic Infiltrate of Jessner. Regular sessions are usually required over several weeks or months.
It is important to note that the effectiveness of treatments may vary from person to person, and a combination of therapies may be necessary to achieve optimal results. It is recommended to consult with a dermatologist or healthcare professional to determine the most suitable treatment plan based on individual circumstances.