Started with spots and itching when I was perhaps 10 years old.Perhaps earlier but that is what I remember for sure.Then nothing more until I was around 30 ,many more spots that made me go to see a Dermatologist. Biopsy and diagnosed, UP.Getting more and more spots and many symptoms that was difficult to find a reason why. Pain,flushing,fatigue , vertigo brain fog weakness headache getting worse and 2007 had bone marrow biopsy and several other examinations, finally diagnosed with Systemic Mastocytos is.