Menetrier disease, also known as giant hypertrophic gastritis, is a rare gastrointestinal disorder that primarily affects the stomach. It is characterized by the enlargement of the gastric mucosa, the inner lining of the stomach, leading to the formation of large folds and deep grooves.
Menetrier disease is typically observed in adults and can cause various symptoms such as abdominal pain, nausea, vomiting, and weight loss. The condition is often associated with excessive production of gastric acid, leading to low levels of protein in the blood and fluid accumulation in the body.
The exact cause of Menetrier disease is unknown, but it is believed to involve an abnormal immune response or a viral infection. It is not considered to be hereditary or contagious.
Diagnosis of Menetrier disease involves a combination of medical history evaluation, physical examination, imaging tests (such as endoscopy and ultrasound), and analysis of stomach tissue samples.
Treatment options for Menetrier disease aim to alleviate symptoms and improve nutritional status. This may include medications to reduce stomach acid production, nutritional support, and in severe cases, surgical removal of the affected portion of the stomach.
Regular follow-up with healthcare professionals is important to monitor the condition and manage any complications that may arise.