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What is Multiple Systems Atrophy

Multiple Systems Atrophy description. Find out what Multiple Systems Atrophy is and know more about it.

What is Multiple Systems Atrophy

Multiple System Atrophy (MSA) is a rare neurodegenerative disorder that affects both the autonomic nervous system (responsible for involuntary bodily functions) and movement. It is characterized by the progressive degeneration of specific areas in the brain, leading to a wide range of symptoms.


MSA is divided into two main subtypes:



  • MSA with predominant parkinsonism (MSA-P): This subtype shares some similarities with Parkinson's disease, including symptoms like tremors, stiffness, and impaired balance.

  • MSA with predominant cerebellar ataxia (MSA-C): This subtype primarily affects coordination and balance, leading to difficulties with walking, coordination, and speech.


Common symptoms of MSA include: orthostatic hypotension (low blood pressure upon standing), urinary dysfunction, constipation, difficulty swallowing, sleep disturbances, and motor impairments.


Unfortunately, there is currently no cure for MSA, and treatment focuses on managing symptoms and improving quality of life. A multidisciplinary approach involving various healthcare professionals is often necessary to address the complex needs of individuals with MSA.


Diseasemaps
3 answers
A progressive neurological disease. It is somewhere between a slow stroke and ALS disease, where over time every system is impacted.

Posted Mar 24, 2018 by [email protected] 3020
Multiple System Atrophy is a serious degenerative neurological disease that affects multiple body systems and quickly robs its victims of the ability to walk, talk, chew, swallow and breathe. There are various symptoms that fall into three general categories: autonomic dysfunction, cerebellar dysfunction and parkinsons-like symptoms. These symptoms can occur in any combination.

You can think of MSA like the three flavored Neapolitan ice cream. Everyone with MSA gets a scoop of the MSA ice cream just as everyone at a birthday party gets a scoop of Neopolitan ice cream in their dish. If you were at the party and looked at your dish and at the dish of the person next to you, you would notice that there is not the exact same amount of vanilla, chocolate and strawberry in both of the dishes.

In someone with Multiple System Atrophy, if their early symptoms are mainly CEREBELLAR like ataxia (loss of balance), slurred speech or difficulty swallowing they have mostly vanilla ice cream in their dish.

If their symptoms are mainly PARKINSONISM like tremors and slowness of movement they have mostly chocolate ice cream in their dish.

If their symptoms are mainly AUTONOMIC like neurogenic orthostatic hypotension or urinary incontinence, urinary retention or sexual dysfunction they have mostly strawberry ice cream in their dish.

Everyone needs to have some strawberry symptoms to have possible MSA.

On top of this they need to have some vanilla and some chocolate symptoms too.

Note that they may have a whole lot of vanilla and a tiny bit of chocolate. If so they are called MSA-C (cerebellar).

If they have a whole lot of chocolate and a tiny bit of vanilla they are called MSA-P (parkinsonism).

People with MSA have a changing bowl of ice cream though, their vanilla and chocolate and strawberry amounts increase over time as they develop more symptoms from the cerebellar or the parkinsons or the autonomic sides but this will vary from person to person. This is because the disease is spreading throughout the brain and is affecting different brain regions. It does not spread exactly the same way in every person.

Posted Mar 31, 2018 by Pam Bower 2952

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Find people with Multiple Systems Atrophy through the map. Connect with them and share experiences. Join the Multiple Systems Atrophy community.

Stories of Multiple Systems Atrophy

MULTIPLE SYSTEMS ATROPHY STORIES
Multiple Systems Atrophy stories
I was a carer to my sister Maureen who passed away from MSA in April 2014. I am more than happy to talk to anyone re: this disease (Multiple System Atrophy) & point them in the right direction for further information, or to just lend an ear if someon...
Multiple Systems Atrophy stories
It didn't seem like much of a disease when it started. I was in my 50s when dizziness arrived, not occasional dizzy spells but an almost constant sense of being on the deck of a boat. I began to stumble once in a while, and later on I had trouble sta...
Multiple Systems Atrophy stories
My story is really my family's story. In 2010, after a year or so of steadily more frequent falls and dropping things and such. Many different Doctor appointments and being told, "You drink too much", "You abused your body too much when you were you...
Multiple Systems Atrophy stories
My mom , Khadija , was diagnosed with Parkinson's disease in 2011 due to difficulty in fine movements like inserting a key into the keyhole in the car. Mom was not responsive to medications prescribed by her neurologists nor did she have a unilateral...
Multiple Systems Atrophy stories
THERE WAS NOTHING UNUSUAL DURING MY CHILDHOOD, OTHER THAN BEING THE OLDEST CHILD WITH TWO ALCOHOLIC PARENTS AND THE RESPONSIBILITY THAT ENTAILS. AS A YOUNG ADULT I PUT MYSELF IS A HIGH STRESS LIFESTYLE. A YOUNG DIVORCEE SINGLE MOM WORKING MULTIPLE J...

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Multiple Systems Atrophy forum

MULTIPLE SYSTEMS ATROPHY FORUM
Multiple Systems Atrophy forum
Does anyone with MSA experience the sensation like you are "bobbing up and down" on a boat?  I experience this most of the time.  It tends to lessen by standing up or laying down!  If so, do you know what it is?   
Multiple Systems Atrophy forum
Anyone with this? Hoe is it? https://clinicaltrials.gov/ct2/show/NCT02388295?term=msa&rank=4
Multiple Systems Atrophy forum
Thanks for adding your marker to the World MSA map. If you know others from the various MSA forums please encourage them to do the same. Did you know... A 57 page booklet of MSA information is available to download from the MSA Coalition website.&nbs...
Multiple Systems Atrophy forum
When: October 14 - 15, 2016 Where: New Orleans, Louisiana, USA Register now and get your FREE ticket at Http://www.MultipleSystemAtrophy.org Tentative Conference Schedule Many thanks to this year’s medical host, David Houghton, M...
Multiple Systems Atrophy forum
Chicago and area MSA support group meeting April 17th 2-4PM Goodwill Crystal Lake - 1016 Central Park Drive, Crystal Lake, IL. Contact John Standley [email protected] 815-403-2221

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