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What is Nephrogenic diabetes insipidus

Nephrogenic diabetes insipidus description. Find out what Nephrogenic diabetes insipidus is and know more about it.

What is Nephrogenic diabetes insipidus

Nephrogenic diabetes insipidus (NDI) is a rare kidney disorder that affects the body's ability to regulate water balance. Unlike diabetes mellitus, NDI is not related to blood sugar control. It is characterized by excessive thirst and urination, similar to diabetes, but the underlying cause is different.


In NDI, the kidneys are unable to respond to a hormone called antidiuretic hormone (ADH) or vasopressin. ADH normally helps the kidneys reabsorb water, reducing urine production. However, in NDI, the kidneys do not properly respond to ADH, leading to the excretion of large volumes of dilute urine.


NDI can be either acquired or inherited. Acquired NDI can result from certain medications, chronic kidney disease, or electrolyte imbalances. Inherited NDI is caused by genetic mutations that affect the function of the kidney tubules.


Common symptoms of NDI include excessive thirst, frequent urination, dehydration, and electrolyte imbalances. Treatment options focus on managing symptoms and preventing complications, such as ensuring adequate fluid intake and using medications to enhance the kidney's response to ADH.


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What is Nephrogenic diabetes insipidus

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NEPHROGENIC DIABETES INSIPIDUS STORIES
Nephrogenic diabetes insipidus stories
My daughter (now 16) has nephrogenic diabetes insipdus since birth. She was diagnosed when she was 4 months old. Until her 7th birthday she got Esidrix and Indometacin. After her 7th birthday she could stop taking the medicine because her body was ab...
Nephrogenic diabetes insipidus stories
My son was born with this condition, he is now 9yrs old   

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