What is Palmoplantar Keratoderma

Palmoplantar Keratoderma (PPK) is a dermatological condition characterized by the thickening of the skin on the palms of the hands and soles of the feet. This condition can be inherited or acquired, and it affects both males and females of all ages.

PPK causes the skin to become excessively thick, rough, and calloused, often leading to discomfort and pain. The affected areas may appear white, yellowish, or brownish, and can develop deep cracks or fissures. The severity of PPK can vary from mild to severe, and it can be a standalone condition or associated with other underlying disorders.

There are several types of PPK, including focal, diffuse, punctate, and palmoplantar keratoderma with associated features. The condition can be caused by genetic mutations, exposure to certain chemicals or irritants, infections, or as a symptom of an underlying medical condition.

Treatment for PPK aims to manage symptoms and improve the quality of life for individuals affected by the condition. This may involve regular moisturization, exfoliation, and the use of keratolytic agents to soften the thickened skin. In severe cases, additional interventions such as topical medications, oral retinoids, or surgical procedures may be necessary.