Pemphigus is a rare autoimmune disorder characterized by the formation of blisters on the skin and mucous membranes. It affects people of all ages, races, and ethnicities, but its prevalence varies across different populations.
According to available data, the prevalence of pemphigus ranges from 0.1 to 5 cases per 100,000 individuals worldwide. Although it is considered a rare disease, it can have a significant impact on the quality of life for those affected.
Pemphigus vulgaris is the most common form of pemphigus, accounting for approximately 70-80% of cases. It is more prevalent in certain ethnic groups, such as Ashkenazi Jews, Mediterranean populations, and individuals of Indian descent. In these populations, the prevalence can be as high as 16 cases per 100,000 individuals.
Pemphigus foliaceus, another subtype of pemphigus, is more prevalent in certain regions, such as Brazil and Tunisia, where it is considered an endemic disease. The prevalence in these areas can reach up to 20 cases per 100,000 individuals.
While pemphigus is a relatively rare condition, its impact on individuals and their families should not be underestimated. Early diagnosis and appropriate treatment are crucial in managing the disease and improving the quality of life for those affected.