Which are the symptoms of Pheochromocytoma?

Symptoms of Pheochromocytoma

Pheochromocytoma is a rare tumor that develops in the adrenal glands, which are located on top of the kidneys. These tumors are usually noncancerous (benign), but they can cause a range of symptoms due to the excessive release of hormones called catecholamines. The symptoms of pheochromocytoma can vary from person to person, and they may come and go. It is important to note that not everyone with this condition will experience all of these symptoms, and some individuals may not have any symptoms at all.

1. High Blood Pressure

One of the hallmark symptoms of pheochromocytoma is high blood pressure (hypertension). The excess release of catecholamines, such as adrenaline and noradrenaline, can cause sudden and severe spikes in blood pressure. These episodes of hypertension can be intermittent and may be accompanied by other symptoms like headache, sweating, and palpitations.

2. Headaches

Headaches are a common symptom of pheochromocytoma. These headaches are often severe and can be throbbing or pulsating in nature. They may be localized to one side of the head or occur on both sides. The headaches may be triggered by sudden changes in blood pressure or physical activity.

3. Sweating

Excessive sweating (diaphoresis) is another common symptom of pheochromocytoma. The sweating may be profuse and unrelated to physical exertion or environmental factors. It can occur during episodes of high blood pressure or even at rest. Night sweats are also possible.

4. Rapid Heartbeat

Pheochromocytoma can cause episodes of rapid heartbeat (tachycardia) or palpitations. The heart may feel like it is racing or pounding. These episodes can be accompanied by a sense of anxiety or panic. The rapid heartbeat may occur spontaneously or be triggered by physical or emotional stress.

5. Tremors

Tremors or shaking of the hands (tremulousness) can occur in individuals with pheochromocytoma. These tremors are usually fine and may be more noticeable during episodes of high blood pressure or anxiety. The tremors may affect one or both hands.

6. Anxiety and Panic Attacks

Feelings of anxiety and panic attacks can be associated with pheochromocytoma. The excessive release of catecholamines can lead to a sense of restlessness, nervousness, and a feeling of impending doom. Panic attacks may occur suddenly and be accompanied by symptoms like shortness of breath, chest pain, and dizziness.

7. Weight Loss

Unexplained weight loss can be a symptom of pheochromocytoma. The increased release of catecholamines can affect metabolism and lead to unintentional weight loss. Individuals may experience a decreased appetite or have difficulty maintaining their usual weight.

8. Abdominal Pain

Some individuals with pheochromocytoma may experience abdominal pain. The pain is typically localized to the upper abdomen and may be intermittent. It can be accompanied by other gastrointestinal symptoms like nausea, vomiting, and diarrhea.

9. Flushing

Episodes of flushing or reddening of the skin can occur in individuals with pheochromocytoma. The flushing may be sudden and affect the face, neck, or upper chest. It can be accompanied by a sensation of warmth or a feeling of heat.

10. Other Symptoms

In addition to the above symptoms, pheochromocytoma can also cause other less common symptoms, including:

• Chest pain


• Shortness of breath


• Constipation


• Weakness or fatigue


• Blurred vision


• Increased thirst


• Increased urination

If you experience any of these symptoms, especially if they are severe or persistent, it is important to consult a healthcare professional for a proper evaluation and diagnosis.