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What is the history of Plasminogen Deficiency (PLGD)?
When was Plasminogen Deficiency (PLGD) discovered? What is the story of this discovery? Was it coincidence or not?
PLG is a protein that is made by the liver. It circulates in the blood. PLG activators convert the protein into plasmin. Plasmin breaks down fibrin, the main protein that clots blood, so normal tissue and healing can occur after injury.
When PLG is reduced, there is less plasmin to break down the fibrin, leading to an abnormally high build-up of fibrin. These fibrin deposits cause swelling in the tissue, resulting in lesions that are characteristic of congenital PLGD.
PLG contributes to normal functioning in the body, allowing new blood vessels to form. It also aids in the development of fertilized eggs during a woman’s pregnancy.
When PLG is reduced, there is less plasmin to break down the fibrin, leading to an abnormally high build-up of fibrin. These fibrin deposits cause swelling in the tissue, resulting in lesions that are characteristic of congenital PLGD.
PLG contributes to normal functioning in the body, allowing new blood vessels to form. It also aids in the development of fertilized eggs during a woman’s pregnancy.
Posted Aug 9, 2017 by jodoinjulie 2000
