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POEMS syndrome synonyms

What other names are the POEMS syndrome known by? Synonyms and other terms with which POEMS syndrome is known.

POEMS syndrome is also known as...

POEMS syndrome, also known as Crow-Fukase syndrome, is a rare multisystem disorder characterized by several distinct features. This condition is named after the key clinical manifestations it encompasses: Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy, and Skin changes.



Polyneuropathy refers to the damage or dysfunction of multiple peripheral nerves, leading to symptoms such as numbness, tingling, weakness, and impaired motor function. It often starts in the lower extremities and gradually progresses upwards.



Organomegaly signifies the abnormal enlargement of organs, particularly the liver, spleen, and lymph nodes. This can cause discomfort, pain, or a feeling of fullness in the affected areas.



Endocrinopathy refers to the dysfunction of various endocrine glands, leading to hormonal imbalances. This can result in symptoms like diabetes, hypothyroidism, adrenal insufficiency, and sexual dysfunction.



Monoclonal gammopathy is characterized by the presence of an abnormal protein called monoclonal gammopathy of undetermined significance (MGUS) in the blood. This protein is produced by abnormal plasma cells and can be detected through laboratory tests.



Skin changes in POEMS syndrome can include hyperpigmentation, thickening, and increased hair growth. These dermatological manifestations are often seen in conjunction with other symptoms.



Other less common features of POEMS syndrome may include edema (fluid retention), Castleman disease (a lymphoproliferative disorder), and thrombocytosis (elevated platelet count).



POEMS syndrome is a complex and challenging condition to diagnose due to its varied symptoms. It primarily affects individuals between the ages of 40 and 60, with men being more commonly affected than women. The exact cause of POEMS syndrome is unknown, but it is believed to involve an overgrowth of plasma cells and the production of abnormal proteins.



Treatment for POEMS syndrome aims to manage the underlying plasma cell disorder, alleviate symptoms, and improve quality of life. Therapeutic approaches may include chemotherapy, radiation therapy, corticosteroids, and supportive care measures.


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Stories of POEMS syndrome

POEMS SYNDROME STORIES
POEMS syndrome stories
First symptoms in the fall of 2007. Had my stem cell transplant in november 2008. It helped a lot, but I still have neuropathy issues.
POEMS syndrome stories
Hi everyone.  So we have quite the story.  When my daughter was 6 months old, my husband hurt his back...or so he thought.  But after much massage therapy and chiro and bedrest, he wasn't improving...finally he got into a neurologist who suspected...
POEMS syndrome stories
It began as a cold toe. After tests were done it was decided that it was a nerve pinched in lowere back region. Chiropractor said with therapy you won't need a back operation. 2012 back operation. Neuropathy getting worse. Saw a neurologist lumber p...

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