What is Polyarteritis Nodosa

Polyarteritis Nodosa (PAN) is a rare autoimmune disease that affects the medium-sized arteries, leading to inflammation and damage. It primarily affects the arteries supplying blood to the muscles, joints, skin, and internal organs.

Symptoms: PAN can cause a wide range of symptoms depending on the organs involved. Common symptoms include fever, fatigue, weight loss, muscle and joint pain, skin rashes, abdominal pain, and nerve problems.

Cause: The exact cause of PAN is unknown, but it is believed to involve an abnormal immune response. It is not contagious or hereditary.

Diagnosis: Diagnosis of PAN involves a combination of medical history, physical examination, blood tests, imaging studies, and sometimes a biopsy of affected tissues.

Treatment: Early diagnosis and treatment are crucial to prevent organ damage. Treatment typically involves a combination of corticosteroids and immunosuppressive drugs to reduce inflammation and suppress the immune system.

Prognosis: The prognosis for PAN varies depending on the severity of organ involvement and the promptness of treatment. With appropriate treatment, many patients can achieve remission and lead a normal life.