Is Polycythemia Vera hereditary?
Here you can see if Polycythemia Vera can be hereditary. Do you have any genetic components? Does any member of your family have Polycythemia Vera or may be more predisposed to developing the condition?
Polycythemia Vera (PV) is a rare blood disorder characterized by the overproduction of red blood cells in the bone marrow. While the exact cause of PV is unknown, it is believed to be caused by acquired genetic mutations rather than being directly inherited. However, there is evidence suggesting a slightly increased risk of developing PV in individuals with a family history of the condition. It is important to consult with a healthcare professional for a comprehensive understanding of the genetic factors involved.
Polycythemia Vera (PV) is a rare blood disorder characterized by the overproduction of red blood cells in the bone marrow. It is considered a myeloproliferative neoplasm, which means it is caused by a mutation in the DNA of bone marrow cells.
When it comes to the hereditary nature of PV, research suggests that there may be a genetic predisposition to developing the condition. However, it is important to note that heredity alone does not determine whether someone will develop PV. In fact, the majority of PV cases are not inherited.
Studies have identified a specific gene mutation called JAK2 V617F that is present in the majority of PV patients. This mutation is acquired during a person's lifetime and is not passed down from parents. However, in rare cases, the JAK2 V617F mutation can be inherited from an affected parent.
It is crucial to understand that even if someone inherits the JAK2 V617F mutation, it does not guarantee the development of PV. Other factors, such as environmental and lifestyle factors, also play a role in the development of the disease.
If there is a family history of PV or other myeloproliferative neoplasms, it is recommended to consult with a healthcare professional or a genetic counselor. They can provide personalized information and guidance based on the individual's specific situation.
Posted Sep 16, 2017 by Patricia 2000
