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How is Primary Biliary Cholangitis diagnosed?

See how Primary Biliary Cholangitis is diagnosed. Which specialists are essential to meet, what tests are needed and other useful information for the diagnosis of Primary Biliary Cholangitis

Primary Biliary Cholangitis diagnosis

Diagnosis of Primary Biliary Cholangitis


Primary Biliary Cholangitis (PBC) is a chronic liver disease that affects the bile ducts in the liver. Early diagnosis is crucial for effective management and treatment. The diagnosis of PBC involves a combination of medical history evaluation, physical examination, blood tests, imaging studies, and liver biopsy.



Medical History Evaluation: The doctor will ask about your symptoms, medical history, and any family history of liver diseases. This helps in understanding the progression and severity of the condition.



Physical Examination: The doctor will perform a physical examination to check for any signs of liver damage, such as jaundice, enlarged liver, or abdominal tenderness.



Blood Tests: Blood tests are essential for diagnosing PBC. The doctor will look for specific antibodies in the blood, such as antimitochondrial antibodies (AMA), which are present in about 95% of PBC cases. Elevated levels of liver enzymes, such as alkaline phosphatase (ALP) and gamma-glutamyl transferase (GGT), may also indicate liver damage.



Imaging Studies: Imaging techniques like ultrasound, magnetic resonance imaging (MRI), or computed tomography (CT) scans may be used to assess the liver's structure and rule out other liver diseases.



Liver Biopsy: In some cases, a liver biopsy may be performed to confirm the diagnosis. A small sample of liver tissue is extracted using a needle and examined under a microscope to assess the extent of liver damage and inflammation.



It is important to consult a healthcare professional if you experience symptoms such as fatigue, itching, abdominal pain, or jaundice. Early diagnosis and treatment can help manage the progression of Primary Biliary Cholangitis and improve long-term outcomes.


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2 answers
Blood Tests, Ultrasound, Fibroscan, Endoscopy, Liver Biopsy

Posted Feb 9, 2020 by Kim 1850

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