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What is the prevalence of Primary Immunodeficiency?

How many people does Primary Immunodeficiency affect? Does it have the same prevalence in men and women? And in the different countries?

Prevalence of Primary Immunodeficiency

The prevalence of Primary Immunodeficiency (PID) varies depending on the specific type. However, overall, PID is considered a rare condition. It is estimated that PID affects approximately 1 in 5,000 to 1 in 10,000 individuals worldwide. Some forms of PID, such as severe combined immunodeficiency (SCID), are even rarer, affecting about 1 in 100,000 to 1 in 200,000 births. Although PID is relatively uncommon, it is crucial to raise awareness about this condition to ensure early diagnosis and appropriate management for affected individuals.



Primary Immunodeficiency (PID) refers to a group of genetic disorders that impair the immune system's ability to fight off infections and diseases. These conditions are typically inherited and can manifest in various ways, affecting both children and adults.


The prevalence of PID varies depending on the specific disorder. However, it is estimated that overall, PID affects approximately 1 in 1,200 to 2,000 individuals worldwide. This prevalence may be higher in certain populations due to genetic factors or consanguineous marriages.


While PID is considered a rare condition, it is important to note that there are over 400 different types of primary immunodeficiencies, each with its own prevalence rate. Some forms of PID, such as selective IgA deficiency, are more common than others.


Early diagnosis and appropriate management are crucial for individuals with PID to prevent severe infections and complications. Genetic testing and consultation with immunology specialists are often necessary to identify and manage these disorders effectively.


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Stories of Primary Immunodeficiency

PRIMARY IMMUNODEFICIENCY STORIES
Primary Immunodeficiency stories
Dana es mi ñieta,despues de 8 años se descubre su inmunodeficiencia, ella padece el DEFICIT DE STAT1,a consecuencia de ello padeció mucho tiempo infecciones a repetición,y ello sumado a impericias médicas que por sobervia no derivaron a centro e...
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My son is 15 and was diagnosed at 3 with iga deficiency and it progressed to iga deficient CVID by the time he was 6...he is holding steady with no IVIG yet... 
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Its kinda a long story. Here's the highlights. Always had sinus problems as a kid. Diagnosed with endometriosis at 17. Lupron, surgery, jump forward to 24 and diagnosed with Stage 4 Burkitts Lymphoma. Post treatment I was always sick. Took 3 years to...
Primary Immunodeficiency stories
hello all, my name is Gabe.  I was diagnosed with CVID in 2014 after passing out in my ENT's office.  I have suffered all my life with severe coughing fits.  To the point were i wouldnt sleep for 3 or 4 days.  My coughing got so bad that i actual...

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