What is Primary Immunodeficiency
Primary Immunodeficiency description. Find out what Primary Immunodeficiency is and know more about it.
Primary Immunodeficiency refers to a group of genetic disorders that weaken the immune system's ability to fight off infections and diseases. Unlike secondary immunodeficiency, which is acquired later in life due to factors like medications or illnesses, primary immunodeficiency is typically present from birth.
Individuals with primary immunodeficiency have a higher susceptibility to infections, which can be more severe and recurrent. Common symptoms include frequent respiratory infections, such as pneumonia or sinusitis, as well as recurring ear infections, skin infections, and gastrointestinal issues.
Primary immunodeficiency disorders are caused by defects in genes responsible for the development and functioning of the immune system. These genetic abnormalities can affect various components of the immune system, including white blood cells, antibodies, or complement proteins.
Diagnosis of primary immunodeficiency involves a thorough medical history, physical examination, and specialized laboratory tests. Treatment options vary depending on the specific disorder but often involve managing symptoms, preventing infections through vaccinations, and in some cases, immune system replacement therapies.
Early detection and proper management of primary immunodeficiency are crucial to minimize complications and improve quality of life for affected individuals.
