PSC is inflammation in the biliary tree of the liver resulting in strictures and narrowing of the ducts. As the ducts close, the liver stops functioning normally. Eventually the damage causes cirrhosis of the liver and the patient will require a liver transplant. There is no known cause or cure, though it is closely linked to inflammatory bowel diseases.

Primary sclerosing cholangitis
Recurring primary sclerosing cholangitis


Digestive system
Digestive system
Immune system
Immune system


  • Upper right quadrant pain
  • Nauseous
  • Vomiting
  • Weight loss
  • Intense itching
  • Jaundice colouring of eyes and skin
  • Enlarged liver
  • Enlarged spleen
  • Fatigue


  • Symptom control
  • Ursodiol
  • Vancomycin
  • Cholestrim powder
  • Liver transplant
  • Specialist who treat it

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    Statistics of Primary Sclerosing Cholangitis

    3 people with Primary Sclerosing Cholangitis have taken the SF36 survey. Mean of Primary Sclerosing Cholangitis is 1798 points (50 %). Total score ranges from 0 to 3,600 being 0 the worst and 3,600 the best. Take the SF36 Survey

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