Progressive multifocal leukoencephalopathy synonyms

Progressive Multifocal Leukoencephalopathy Synonyms

Progressive Multifocal Leukoencephalopathy (PML) is a rare and potentially fatal viral infection that affects the central nervous system. It is caused by the JC virus, which is a common virus that is usually harmless in healthy individuals. However, in people with weakened immune systems, such as those with HIV/AIDS or those taking immunosuppressive medications, the JC virus can cause PML.

PML is characterized by the destruction of the myelin, the protective covering of nerve cells in the brain. This leads to a range of neurological symptoms, including weakness, loss of coordination, changes in vision, and cognitive decline. The progression of PML can be rapid, and it often leads to severe disability or death.

While "Progressive Multifocal Leukoencephalopathy" is the official medical term for this condition, there are several synonyms that are commonly used to refer to PML:

• Progressive Multifocal Encephalopathy: This term is often used interchangeably with PML. Encephalopathy refers to a disease or disorder of the brain.


• JC Virus Encephalopathy: Since PML is caused by the JC virus, this term highlights the viral origin of the condition.


• Progressive Leukoencephalopathy: This term emphasizes the progressive nature of the disease and the involvement of the white matter in the brain.


• Progressive Multifocal Cerebral Demyelination: This synonym describes the demyelination process that occurs in PML, where the myelin is damaged or destroyed.

It is important to note that while these terms are often used interchangeably, they all refer to the same condition: Progressive Multifocal Leukoencephalopathy.