Prolactinoma is a benign tumor of the pituitary gland that causes excessive production of the hormone prolactin. This condition primarily affects women, but can also occur in men. Prolactinoma can lead to a variety of symptoms, including irregular menstrual periods, infertility, decreased libido, breast milk production in non-pregnant women, and erectile dysfunction in men.
While there is no definitive cure for prolactinoma, it can be effectively managed with appropriate treatment. The main goal of treatment is to reduce prolactin levels and alleviate symptoms. Medications called dopamine agonists, such as cabergoline or bromocriptine, are commonly prescribed to lower prolactin levels and shrink the tumor. These medications work by mimicking the action of dopamine, a neurotransmitter that inhibits prolactin secretion.
In most cases, long-term treatment with dopamine agonists can effectively control prolactinoma. Regular monitoring of prolactin levels and tumor size through blood tests and imaging studies is necessary to assess treatment response and adjust medication dosage if needed. It is important to continue treatment even if symptoms improve or disappear, as stopping medication prematurely may result in tumor regrowth and recurrence of symptoms.
In some cases, surgery or radiation therapy may be considered if medication therapy fails or if the tumor is large and causing significant complications. Surgery involves removing the tumor through the nose or skull, while radiation therapy uses high-energy beams to destroy tumor cells. These interventions are typically reserved for cases where medication therapy is ineffective or not well-tolerated.
It is important for individuals with prolactinoma to work closely with their healthcare team to develop an individualized treatment plan. Regular follow-up appointments and adherence to prescribed medications are crucial for long-term management of the condition. With appropriate treatment and monitoring, most individuals with prolactinoma can lead normal, healthy lives.