What is the prevalence of Prune Belly Syndrome?

Prune Belly Syndrome, also known as Eagle-Barrett syndrome, is a rare congenital disorder that primarily affects males. It is characterized by a triad of symptoms: absence or severe underdevelopment of the abdominal muscles, undescended testicles, and urinary tract abnormalities. The exact prevalence of Prune Belly Syndrome is difficult to determine due to its rarity and varying degrees of severity.

However, studies estimate that Prune Belly Syndrome occurs in approximately 1 in 30,000 to 1 in 40,000 live births. It is important to note that the syndrome predominantly affects males, with a male-to-female ratio of about 30:1. The cause of Prune Belly Syndrome is not fully understood, but it is believed to result from a combination of genetic and environmental factors.

Prune Belly Syndrome can have significant implications for affected individuals, including challenges with kidney function, urinary tract infections, and gastrointestinal issues. Early diagnosis and comprehensive medical management are crucial in improving outcomes for individuals with this syndrome.

While Prune Belly Syndrome is considered rare, it is essential for healthcare professionals and families to be aware of its existence and the potential complications associated with it. Ongoing research and support networks aim to enhance understanding and provide better care for individuals living with Prune Belly Syndrome.