What are the best treatments for Prune Belly Syndrome?

Treatments for Prune Belly Syndrome

Prune Belly Syndrome, also known as Eagle-Barrett syndrome, is a rare congenital disorder that primarily affects males. It is characterized by a triad of symptoms including absence or severe underdevelopment of the abdominal muscles, undescended testicles, and urinary tract abnormalities. While there is no cure for Prune Belly Syndrome, there are several treatments available to manage the condition and improve the quality of life for affected individuals.

1. Surgical Interventions

Surgery plays a crucial role in the treatment of Prune Belly Syndrome. It is often necessary to correct the urinary tract abnormalities and undescended testicles. Surgical procedures may include:

• Urinary tract reconstruction: This involves reconstructing the urinary tract to improve urine flow and prevent complications such as urinary tract infections and kidney damage.


• Orchiopexy: This procedure is performed to bring the undescended testicles into the scrotum, allowing for normal development and function.


• Abdominal wall reconstruction: In severe cases, surgery may be required to reconstruct the abdominal wall and improve its functionality.

2. Medications

Medications may be prescribed to manage specific symptoms associated with Prune Belly Syndrome:

• Antibiotics: Frequent urinary tract infections are common in individuals with Prune Belly Syndrome. Antibiotics may be prescribed to treat and prevent these infections.


• Medications for bladder function: Some individuals may require medications to improve bladder function and control.

3. Nutritional Support

Proper nutrition is essential for individuals with Prune Belly Syndrome to support growth and development. A registered dietitian can help develop a personalized nutrition plan that meets the specific needs of the individual.

4. Supportive Care

Prune Belly Syndrome can have a significant impact on the physical and emotional well-being of affected individuals. Supportive care is crucial and may include:

• Regular follow-up appointments: Regular check-ups with healthcare professionals are necessary to monitor the progress of the condition and address any emerging issues.


• Psychological support: Prune Belly Syndrome may cause emotional distress. Counseling or therapy can help individuals and their families cope with the challenges associated with the condition.


• Support groups: Connecting with other individuals and families affected by Prune Belly Syndrome can provide valuable support, information, and a sense of community.

It is important to note that the treatment approach for Prune Belly Syndrome may vary depending on the severity of the condition and individual needs. A multidisciplinary team of healthcare professionals, including urologists, surgeons, nephrologists, and geneticists, is typically involved in the management of Prune Belly Syndrome to provide comprehensive care.