What is Refractory Celiac Disease

Refractory Celiac Disease (RCD) is a rare and severe form of celiac disease, an autoimmune disorder triggered by the ingestion of gluten. While most individuals with celiac disease can manage their symptoms by following a gluten-free diet, RCD refers to cases where the symptoms persist or worsen despite strict adherence to this diet.

RCD occurs when the immune system continues to attack the lining of the small intestine, leading to inflammation and damage. This can result in persistent gastrointestinal symptoms such as diarrhea, abdominal pain, and malabsorption of nutrients. If left untreated, RCD can lead to serious complications, including nutrient deficiencies, osteoporosis, and an increased risk of intestinal lymphoma.

Diagnosing RCD involves ruling out other possible causes of symptoms and conducting specialized tests, such as examining the intestinal tissue for abnormal cells. Treatment options for RCD are limited, and a multidisciplinary approach involving gastroenterologists, dietitians, and other specialists is often necessary. In some cases, medications to suppress the immune system may be prescribed to manage symptoms and reduce inflammation.

Overall, RCD is a challenging condition that requires ongoing medical management and support to improve quality of life for affected individuals.