Sclerosing Mesenteritis is a rare inflammatory condition affecting the mesentery, a tissue that supports the intestines. The prognosis and life expectancy for individuals with this condition can vary widely. Some cases may remain stable for years with minimal symptoms, while others may experience progressive disease and complications. There is limited data available on the average life expectancy for individuals with Sclerosing Mesenteritis. It is crucial for patients to work closely with their healthcare team to manage symptoms, monitor disease progression, and address any complications that may arise. Early diagnosis, appropriate treatment, and regular follow-up can help optimize the quality of life for individuals with this condition.