What is the prevalence of Sirenomelia?
How many people does Sirenomelia affect? Does it have the same prevalence in men and women? And in the different countries?
Sirenomelia, also known as mermaid syndrome, is an extremely rare congenital malformation. It is estimated to occur in approximately 1 in every 60,000 to 100,000 births worldwide. This condition is characterized by the fusion of the lower limbs, resulting in a single lower extremity resembling a mermaid's tail. Sirenomelia is often associated with severe abnormalities in the internal organs, such as kidney, bladder, and gastrointestinal defects. The exact cause of sirenomelia remains unknown, and the prognosis for affected individuals is generally poor. Early diagnosis and multidisciplinary medical care are crucial for managing this complex condition.
Sirenomelia, also known as mermaid syndrome, is an extremely rare congenital malformation that affects approximately 1 in every 60,000 to 100,000 births. It is characterized by the fusion of the lower limbs, resulting in a single lower extremity resembling a mermaid's tail. This condition is typically accompanied by severe abnormalities in the internal organs, including the urinary and gastrointestinal systems.
The exact cause of sirenomelia remains unknown, but several factors such as genetic and environmental influences have been suggested. The condition is more commonly observed in infants of mothers with diabetes, suggesting a potential link between maternal health and the development of sirenomelia.
Sirenomelia is a life-threatening condition, and most affected infants do not survive beyond the neonatal period. The complex nature of the associated abnormalities makes treatment challenging, and management often involves a multidisciplinary approach involving pediatric surgeons, neonatologists, and other specialists.
Given its rarity and the significant medical challenges it presents, sirenomelia requires further research and awareness to improve understanding, early detection, and potential treatment options.
