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What is the prevalence of Small Fiber Neuropathy?

How many people does Small Fiber Neuropathy affect? Does it have the same prevalence in men and women? And in the different countries?

Prevalence of Small Fiber Neuropathy

Small Fiber Neuropathy (SFN) is a relatively common disorder affecting the small nerve fibers in the peripheral nervous system. While exact prevalence rates are challenging to determine due to underdiagnosis, it is estimated that SFN affects approximately 3-5% of the general population. SFN can be caused by various factors, including diabetes, autoimmune diseases, and genetic mutations. Symptoms may include pain, tingling, and numbness in the affected areas. Early diagnosis and management are crucial for preventing further nerve damage and improving quality of life for individuals with SFN.



Small Fiber Neuropathy (SFN) is a relatively common disorder affecting the peripheral nervous system. It is characterized by damage to the small nerve fibers responsible for transmitting sensory information, leading to various symptoms.


The prevalence of SFN varies depending on the population studied and the diagnostic criteria used. However, research suggests that SFN is not uncommon, with estimates ranging from 52 to 364 cases per 100,000 individuals. It is important to note that SFN is often underdiagnosed or misdiagnosed due to its diverse symptoms and lack of awareness among healthcare professionals.


Common symptoms of SFN include: burning or tingling sensations, numbness, pain, and hypersensitivity to touch or temperature changes. These symptoms typically affect the hands and feet but can also involve other areas of the body.


While the exact cause of SFN is often unknown, it can be associated with various underlying conditions such as diabetes, autoimmune disorders, infections, and genetic mutations.


Early diagnosis and appropriate management are crucial to prevent further nerve damage and improve quality of life for individuals with SFN. If you suspect you may have SFN, it is important to consult a healthcare professional for proper evaluation and guidance.


Diseasemaps
3 answers
In 2013 the NIH put SFN prevalence at 52 cases her 100,000 people which is about .05% of the population, but since then there has been more and better testing so that number has likely increased.

Posted Jul 12, 2021 by Jo 3150
According to Harvard and Stanford Neurology and UCSF, 1 in 1,000,000

Posted Feb 3, 2022 by Mark 2000

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Small Fiber Neuropathy forum

SMALL FIBER NEUROPATHY FORUM
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How many of you developed your neuropathy after taking Fluoroquinolone antibiotics? (Cipro, Avelox, Levaquin) There is a map here for Fluoroquinolone Toxicity now, too.
Small Fiber Neuropathy forum
Anyone have non-diabetic small fiber neuropathy? Have your doctors found a cause or is it idiopathic?
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What kind of treatment options are there for small fiber neuropathy? Are they helpful?

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