What is the prevalence of Stargardt Disease?

Stargardt Disease, also known as Stargardt macular dystrophy or juvenile macular degeneration, is a genetic eye disorder that primarily affects the macula, the central part of the retina responsible for sharp, detailed vision. It is typically diagnosed in childhood or adolescence, leading to progressive vision loss over time.

The prevalence of Stargardt Disease varies across different populations. According to current estimates, it affects approximately 1 in every 8,000 to 10,000 individuals worldwide. However, it is important to note that prevalence rates may differ among different ethnic groups and geographical regions.

Stargardt Disease is inherited in an autosomal recessive manner, meaning that both parents must carry a mutated gene for their child to develop the condition. The disease is caused by mutations in the ABCA4 gene, which plays a crucial role in the recycling of a molecule called retinoid in the retina.

While there is currently no cure for Stargardt Disease, ongoing research aims to develop potential treatments to slow down or halt its progression. Early diagnosis and regular monitoring by eye care professionals are essential for managing the condition and providing appropriate support to individuals affected by this genetic eye disorder.