I was dxed with MGUS in 2008 by a nephrologist that I was referred to because of an e-GFR result. I progressed to Waldenstroms in 2014 after investigating my PN at MAYO. My PN is Anti-MAG. I was treated with Rituxan in January of 2015. I have had setbacks in my neuropathy, which since resolved to my 2014 status. My IgM continues to drop, currently at 451mg . Of interest , I have a sister who has MGUS. Also I found an old lab result from 1975 showing an elevated IGM, which was considered "essentially normal" at that time.