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What is the prevalence of Subacute Sclerosing Panencephalitis?

How many people does Subacute Sclerosing Panencephalitis affect? Does it have the same prevalence in men and women? And in the different countries?

Prevalence of Subacute Sclerosing Panencephalitis

Subacute Sclerosing Panencephalitis (SSPE) is a rare neurological disorder caused by a persistent infection of the measles virus. It primarily affects individuals who have had measles in the past. The prevalence of SSPE is estimated to be approximately 1 in every 100,000 to 1 in every 1,700,000 individuals worldwide. Although considered rare, it is a devastating condition with a high mortality rate. Early diagnosis and intervention are crucial for managing the symptoms and improving outcomes. Vaccination against measles remains the most effective preventive measure against SSPE.



Subacute Sclerosing Panencephalitis (SSPE) is a rare and devastating neurological disorder caused by persistent infection with the measles virus. It primarily affects children and young adults who have previously had measles, typically occurring several years after the initial infection.


The prevalence of SSPE is relatively low, with estimates varying across different populations. In developed countries where measles vaccination is widespread, the prevalence is estimated to be around 1 in 100,000 to 1 in 1,700,000 individuals. However, in regions with lower vaccination rates or limited access to healthcare, the prevalence can be higher.


Although SSPE is considered rare, it is important to note that the consequences of the disease can be severe. The condition progresses slowly, leading to neurological deterioration, cognitive decline, seizures, and ultimately death. Unfortunately, there is no cure for SSPE, and treatment options are limited to managing symptoms and providing supportive care.


Early recognition and prevention through measles vaccination are crucial in reducing the prevalence of SSPE. Vaccination not only protects individuals from measles but also helps prevent the potential development of SSPE later in life.


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