What is the history of Superior Mesenteric Artery Syndrome?

Superior Mesenteric Artery Syndrome (SMAS) is a rare condition characterized by compression of the third part of the duodenum (the first part of the small intestine) between the superior mesenteric artery (SMA) and the abdominal aorta. This compression leads to various gastrointestinal symptoms and can result in severe complications if left untreated.

The history of SMAS dates back to the early 20th century when it was first described by Carl Freiherr von Rokitansky, an Austrian pathologist, in 1861. However, it wasn't until 1927 that the term "Superior Mesenteric Artery Syndrome" was coined by Wilkie, a British surgeon, who reported a series of cases with similar symptoms.

The underlying cause of SMAS is the narrowing of the angle between the SMA and the aorta, resulting in compression of the duodenum. This narrowing can occur due to various factors, including rapid weight loss, prolonged bed rest, scoliosis, trauma, or surgical procedures that alter the anatomy of the abdomen.

The symptoms of SMAS can vary in severity and may include:

• Abdominal pain: The most common symptom of SMAS is severe, crampy abdominal pain, typically located in the upper abdomen.


• Nausea and vomiting: Due to the obstruction of the duodenum, patients may experience frequent episodes of nausea and vomiting.


• Weight loss: SMAS can lead to significant weight loss due to the inability to tolerate adequate food intake.


• Early satiety: Patients may feel full after consuming only small amounts of food.


• Malnutrition: If left untreated, SMAS can result in malnutrition and its associated complications.

Diagnosing SMAS can be challenging as the symptoms can mimic other gastrointestinal disorders. Medical history, physical examination, and imaging studies are crucial in making an accurate diagnosis. Imaging techniques such as barium swallow studies, computed tomography (CT) scans, and magnetic resonance imaging (MRI) can help visualize the compression of the duodenum and confirm the diagnosis.

Treatment options for SMAS depend on the severity of symptoms and the underlying cause. Initially, conservative management is attempted, which includes nutritional support, weight gain, and correction of any underlying factors contributing to the condition. This may involve dietary modifications, such as small, frequent meals, and a high-calorie diet. In some cases, enteral or parenteral nutrition may be necessary to ensure adequate nutrition.

If conservative measures fail or if the condition is severe, surgical intervention may be required. The most common surgical procedure for SMAS is called a duodenojejunostomy, where a bypass is created to relieve the duodenal obstruction. This procedure allows food to bypass the compressed area and reach the jejunum, restoring normal gastrointestinal function.

Prognosis for patients with SMAS varies depending on the severity of the condition and the promptness of diagnosis and treatment. With early recognition and appropriate management, most patients experience significant improvement in symptoms and quality of life. However, delayed diagnosis or inadequate treatment can lead to complications such as malnutrition, dehydration, and even death.

In conclusion, Superior Mesenteric Artery Syndrome is a rare condition characterized by the compression of the duodenum between the superior mesenteric artery and the abdominal aorta. It was first described in the 19th century and has since been recognized as a distinct clinical entity. Prompt diagnosis and appropriate management are crucial in ensuring favorable outcomes for patients with SMAS.