What is the prevalence of Sweet Syndrome?

Sweet Syndrome, also known as acute febrile neutrophilic dermatosis, is a rare inflammatory skin condition characterized by the sudden onset of fever, painful skin lesions, and an increase in white blood cell count. The exact prevalence of Sweet Syndrome is not well-established, as it is considered a rare disorder. However, it is estimated to affect approximately 3 individuals per million population per year, making it relatively uncommon.

Sweet Syndrome can occur in individuals of any age, but it is most commonly diagnosed in adults between the ages of 30 and 60. It can be associated with various underlying conditions such as infections, autoimmune diseases, malignancies, and certain medications. The exact cause of Sweet Syndrome is not fully understood, but it is believed to involve an abnormal immune response.

The diagnosis of Sweet Syndrome is primarily based on clinical presentation, skin biopsy, and exclusion of other potential causes. Treatment typically involves addressing the underlying condition, if present, and the use of systemic corticosteroids to reduce inflammation and alleviate symptoms.

While Sweet Syndrome is a rare condition, it is important for healthcare professionals to be aware of its existence and consider it in the differential diagnosis of patients presenting with characteristic symptoms and skin lesions.