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How is Trench Fever diagnosed?

See how Trench Fever is diagnosed. Which specialists are essential to meet, what tests are needed and other useful information for the diagnosis of Trench Fever

Trench Fever diagnosis

Trench fever is a bacterial infection caused by the bacterium Bartonella quintana. It was first identified during World War I when it affected soldiers living in unsanitary conditions in trenches. Today, it is still occasionally seen in homeless populations and individuals with poor living conditions.


Diagnosing trench fever can be challenging as its symptoms can be similar to other diseases. A thorough medical history and physical examination are essential for accurate diagnosis. The doctor will inquire about the patient's symptoms, recent travel history, and exposure to unsanitary conditions.


Key diagnostic tests that can aid in confirming trench fever include:



  • Blood tests: A complete blood count (CBC) may reveal an elevated number of white blood cells, particularly the type called neutrophils. Additionally, a blood culture may be performed to identify the presence of Bartonella quintana bacteria.

  • Serology: This test involves checking for the presence of specific antibodies against Bartonella quintana in the blood. A positive serology result indicates a current or past infection.

  • PCR testing: Polymerase chain reaction (PCR) testing can detect the genetic material of Bartonella quintana in blood samples. This method is highly sensitive and specific for diagnosing trench fever.


Other considerations that can aid in the diagnosis of trench fever include:



  • Symptom evaluation: Trench fever typically presents with symptoms such as recurrent fever, severe headache, muscle and joint pain, and fatigue. These symptoms, along with a history of exposure to unsanitary conditions, can raise suspicion for trench fever.

  • Response to treatment: If a patient responds well to antibiotics commonly used to treat trench fever, such as doxycycline or azithromycin, it can further support the diagnosis.


It is important to consult a healthcare professional for an accurate diagnosis and appropriate treatment if trench fever is suspected. Prompt diagnosis and treatment can help alleviate symptoms and prevent complications.


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