Tricho Dento Osseous Syndrome (TDO) prevalence:
Tricho Dento Osseous Syndrome is a rare genetic disorder characterized by abnormalities in hair, teeth, and bones. The exact prevalence of TDO is not well-established due to its rarity and underdiagnosis. However, it is estimated to affect approximately 1 in every 1,000,000 individuals worldwide. TDO can manifest differently in each affected individual, making diagnosis challenging. Genetic testing and clinical evaluation are crucial for accurate diagnosis. Early detection and management of TDO can help improve the quality of life for individuals living with this syndrome.
Tricho Dento Osseous Syndrome (TDO) is a rare genetic disorder that affects the development of hair, teeth, and bones. It is characterized by distinctive facial features, such as a prominent forehead, a broad nasal bridge, and a wide mouth. TDO can also cause abnormalities in the hair, including sparse or absent eyebrows and eyelashes.
The prevalence of TDO is not well-documented, but it is considered to be a rare condition. The exact number of individuals affected by TDO is unknown, as it is often underdiagnosed or misdiagnosed due to its rarity and variable presentation. However, it is estimated that TDO occurs in approximately 1 in every 1 million people.
TDO is typically inherited in an autosomal dominant manner, meaning that an affected individual has a 50% chance of passing the condition on to each of their children. However, sporadic cases can also occur, where there is no family history of the syndrome.
Diagnosis of TDO is based on clinical features, dental and radiographic findings, and genetic testing. Treatment focuses on managing the symptoms and complications associated with the syndrome, such as dental abnormalities and bone fractures.