Medications can be used to treat trichotillomania. Treatment with clomipramine, a tricyclic antidepressant, was shown in a small double-blind study to improve symptoms, but results of other studies on clomipramine for treating trichotillomania have been inconsistent. Naltrexone may be a viable treatment. Fluoxetine and other selective serotonin reuptake inhibitors (SSRIs) have limited usefulness in treating trichotillomania, and can often have significant side effects. Behavioral therapy has proven more effective when compared to fluoxetine or control groups. There is little research on the effectiveness of both behavioral therapy together with medication, and robust evidence from high-quality studies is lacking. Acetylcysteine treatment stemmed from an understanding of glutamate's role in regulation of impulse control.
Emily Kight, 27, from Philadelphia invented a topical lotion that she claims cured her condition. Others find the use of aversion therapy, such as Pavlok wearable devices, cured their disorder. The wearable is a bracelet with motion detection that vibrates if it notices you performing your behavior. It also has an optional electric shock with various strengths that are designed to train your brain to associate the act of rubbing or pulling with negative stimulus, rather than the relief that many afflicted feel after pulling out a hair. Other such awareness bracelets exist, such as Keen (HabitAware) and Slightly Robot, minus the electric shock.
Fidget toys and stress toys have become increasingly popular as well and help ease the urge to pull for many Trich sufferers.