Typhoid fever is a significant global health concern, particularly in regions with inadequate sanitation and limited access to clean water. It is caused by the bacterium Salmonella enterica serotype Typhi, which is primarily transmitted through contaminated food and water.
The prevalence of typhoid fever varies across different parts of the world. According to the World Health Organization (WHO), an estimated 11-21 million cases occur annually, resulting in approximately 128,000-161,000 deaths. The majority of these cases are reported in low- and middle-income countries, particularly in South Asia, Southeast Asia, and sub-Saharan Africa.
Factors contributing to the prevalence of typhoid fever include poor sanitation, inadequate hygiene practices, and limited access to safe drinking water. Overcrowded urban areas with inadequate sewage systems are particularly vulnerable to outbreaks. Additionally, international travel can contribute to the spread of the disease.
Efforts to combat typhoid fever include improving sanitation infrastructure, promoting hygiene practices, and increasing access to safe water sources. Vaccination campaigns targeting high-risk populations have also proven effective in reducing the burden of the disease.