Living with Tyrosinemia Type II

Tyrosinemia Type II, also known as tyrosinemia with transient tyrosinemia, is a rare genetic disorder that affects the body's ability to break down the amino acid tyrosine. This condition is caused by a deficiency of the enzyme tyrosine aminotransferase (TAT), which is responsible for converting tyrosine into other compounds that the body can use.

Diagnosis and Treatment

Diagnosing Tyrosinemia Type II typically involves a combination of clinical evaluation, biochemical testing, and genetic analysis. Symptoms may vary, but common signs include failure to thrive, liver dysfunction, and developmental delays. If you suspect you or your child may have Tyrosinemia Type II, it is important to consult with a healthcare professional for proper diagnosis and management.

While there is no cure for Tyrosinemia Type II, the condition can be managed through dietary modifications and medical interventions. The primary goal of treatment is to reduce the levels of tyrosine and its byproducts in the body, as their accumulation can lead to liver and kidney damage.

Dietary Modifications

A low-protein diet is typically recommended for individuals with Tyrosinemia Type II. This involves restricting the intake of foods high in tyrosine, such as meat, fish, dairy products, and certain grains. Instead, emphasis is placed on consuming foods low in tyrosine, such as fruits, vegetables, and some grains.

Medical formulas that are specifically designed for individuals with Tyrosinemia Type II may also be prescribed. These formulas are low in tyrosine and provide the necessary nutrients for growth and development.

Medical Interventions

In addition to dietary modifications, individuals with Tyrosinemia Type II may require medical interventions to manage their condition effectively. This may include the use of medications to help reduce tyrosine levels or to support liver function.

Regular monitoring of tyrosine levels, liver function, and overall health is crucial for individuals with Tyrosinemia Type II. This allows healthcare professionals to adjust treatment plans as needed and ensure optimal management of the condition.

Support and Lifestyle

Living with Tyrosinemia Type II can present challenges, but with proper management and support, individuals can lead fulfilling lives. Here are some tips to help:

• Educate yourself: Learn as much as you can about Tyrosinemia Type II, its symptoms, and treatment options. This knowledge will empower you to make informed decisions and advocate for your health.


• Follow the recommended diet: Stick to the low-protein diet prescribed by your healthcare team. This will help control tyrosine levels and minimize the risk of complications.


• Stay connected: Join support groups or connect with others who have Tyrosinemia Type II. Sharing experiences and advice can provide emotional support and practical tips for managing the condition.


• Regular check-ups: Attend scheduled medical appointments to monitor your health and ensure early detection of any potential issues.


• Communicate with your healthcare team: Keep an open line of communication with your healthcare professionals. Discuss any concerns or changes in symptoms promptly.


• Live a balanced lifestyle: While managing Tyrosinemia Type II is important, it is also essential to focus on overall well-being. Engage in activities you enjoy, maintain a healthy sleep routine, and manage stress levels.

Remember, every individual's experience with Tyrosinemia Type II is unique. It is essential to work closely with your healthcare team to develop a personalized management plan that suits your specific needs.