Von Willebrand Disease, also known as VWD, is a genetic disorder that affects the blood's ability to clot properly. It is named after Erik Adolf von Willebrand, a Finnish physician who first described the condition in the 1920s. VWD is caused by a deficiency or dysfunction of von Willebrand factor (VWF), a protein that plays a crucial role in the clotting process.
Synonyms for Von Willebrand Disease include:
VWD is characterized by prolonged bleeding, easy bruising, and in some cases, excessive bleeding after surgery or injury. The severity of the condition can vary widely, ranging from mild to severe. Individuals with VWD may experience nosebleeds, heavy or prolonged menstrual periods, and gastrointestinal bleeding.
Diagnosis of VWD involves:
Treatment for VWD aims to prevent or control bleeding episodes. This may involve:
It is important for individuals with VWD to work closely with their healthcare providers to develop a personalized treatment plan and to take necessary precautions to avoid bleeding complications.