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What is the prevalence of Waldenstrom Macroglobulinemia?

How many people does Waldenstrom Macroglobulinemia affect? Does it have the same prevalence in men and women? And in the different countries?

Prevalence of Waldenstrom Macroglobulinemia

Waldenstrom Macroglobulinemia is a rare type of non-Hodgkin lymphoma characterized by the overproduction of abnormal white blood cells called lymphoplasmacytic cells. It accounts for approximately 1-2% of all lymphomas. The prevalence of this condition is estimated to be around 3-4 cases per million people worldwide. Although it is considered a rare disease, it primarily affects older individuals, with the median age at diagnosis being around 70 years. The exact cause of Waldenstrom Macroglobulinemia is unknown, and it typically progresses slowly, leading to various symptoms such as fatigue, anemia, and enlarged lymph nodes.



Waldenstrom Macroglobulinemia (WM) is a rare type of non-Hodgkin lymphoma characterized by the overproduction of abnormal white blood cells called lymphoplasmacytic cells. While it is considered a rare disease, the exact prevalence of WM is not well-established due to its rarity and the lack of comprehensive population-based studies.



However, it is estimated that WM accounts for approximately 1-2% of all hematologic malignancies. The incidence of WM varies across different regions and populations, with slightly higher rates reported in Western countries. It predominantly affects older individuals, with the median age at diagnosis being around 70 years.



WM is slightly more common in men than in women, and there is a higher incidence among Caucasians compared to other ethnic groups. It is important to note that these statistics are general estimates and may vary based on specific populations and geographical locations.



Early diagnosis and appropriate management are crucial for improving outcomes in WM patients. If you suspect any symptoms or have concerns about Waldenstrom Macroglobulinemia, it is essential to consult a healthcare professional for proper evaluation and guidance.


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2 answers
It is about 3 in a million. It's quite rare

Posted Sep 8, 2017 by Lynda 1300

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Stories of Waldenstrom Macroglobulinemia

WALDENSTROM MACROGLOBULINEMIA STORIES
Waldenstrom Macroglobulinemia stories
DECEMBER 22, 2015 - I was diagnosed in March 2007 at age 55 after a routine blood test showed anemia, and follow-up tests found hyperviscosity syndrome. IgM was 62, which is 6200 in US units. Hematologist said I would need treatment in a matter of mo...
Waldenstrom Macroglobulinemia stories
_I WAS DIAGNOSED  NEARLY 3 YEARS AGO WHEN A BLOOD TEST FOR SOMETHING ELSE SHOWED A HIGH IGM.  HAD 2 ROUNDS OF CHEMO (VELCADE) AND HAD SOME BAD SIDE EFFECTS.  AFTER A SECOND OPINION AT THE JAMES CANCER CENTER IN COLUMBUS, OHIO  IT WAS DETERMINED I...
Waldenstrom Macroglobulinemia stories
    I was dxed with MGUS in 2008 by a nephrologist that I was referred to because of an e-GFR result. I progressed to Waldenstroms in 2014 after investigating my PN at MAYO. My PN is Anti-MAG. I was treated with Rituxan in January of 2015. I have...
Waldenstrom Macroglobulinemia stories
spring 2014 sudden weight loss (2 stone) anaemic night sweats waekness; doctors went down gastric route until heart started to fail: superb consultant asked for tests in jan 15; even then had to spend a few months learning i had kidney cancer. in ...
Waldenstrom Macroglobulinemia stories
My husband was diagnosed with WM in mid 2014. He has been in the watchful waiting mode. At his last onc appointment he has been told he needs to start treatment. He has been trying to heal his body with nutrition and supplements and is terrified of c...

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