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What is the history of Wolff-Parkinson-White syndrome?

When was Wolff-Parkinson-White syndrome discovered? What is the story of this discovery? Was it coincidence or not?

History of Wolff-Parkinson-White syndrome


Wolff-Parkinson-White (WPW) syndrome is a relatively rare cardiac disorder that was first described in the medical literature in the early 20th century. It is named after the two physicians who independently reported cases of this condition: Dr. Louis Wolff and Dr. John Parkinson. Their groundbreaking work paved the way for further understanding and advancements in the diagnosis and treatment of WPW syndrome.



The history of WPW syndrome dates back to the 1930s when Dr. Louis Wolff, an American cardiologist, observed a unique electrocardiogram (ECG) pattern in a patient with paroxysmal tachycardia. He noticed the presence of an abnormal electrical pathway in the heart that caused rapid heart rates. Dr. Wolff published his findings in 1930, describing the condition as a "bundle-branch block with short P-R interval."



Around the same time, in 1933, Dr. John Parkinson, a British physician, independently reported similar cases of patients with rapid heart rates and abnormal ECG patterns. He referred to the condition as "atrioventricular bundle extrasystole." Dr. Parkinson's work further contributed to the understanding of this syndrome.



Over the following decades, more research was conducted to elucidate the underlying mechanisms and clinical implications of WPW syndrome. In the 1960s, Dr. Paul Dudley White, an American cardiologist, made significant contributions to the field. He recognized that the abnormal electrical pathway in WPW syndrome involved an accessory pathway called the "Bundle of Kent," which bypassed the normal electrical conduction system of the heart.



The development of catheterization techniques in the 1970s revolutionized the diagnosis and treatment of WPW syndrome. Cardiologists could now directly visualize and map the abnormal electrical pathways in the heart. This breakthrough allowed for the identification of specific locations of the accessory pathways and facilitated the use of catheter ablation as a curative treatment for WPW syndrome.



In recent years, advancements in genetic research have shed light on the hereditary nature of WPW syndrome. Several genes associated with the condition have been identified, providing insights into its pathogenesis and potential targets for future therapies.



Today, WPW syndrome is recognized as a relatively rare but important cardiac disorder. It is characterized by episodes of rapid heart rates, known as paroxysmal supraventricular tachycardia, which can lead to palpitations, dizziness, and in severe cases, life-threatening arrhythmias. Early diagnosis and appropriate management, including catheter ablation, have significantly improved the prognosis for individuals with WPW syndrome.


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I was born in 2014 at 26 weeks weighing 630g.  I had 1 episode of SVT and diagnosed with WPW in August 2014 and have been on propranolol ever since.  If anyone can help my mummy and daddy understand this disease better and what it's like living wi...
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One day i was going to college when my heart started beating too fast. I didn't understand anything and I was terrified. I went to a clinic, they diagnosed  me to tell me that I was born with a very rare syndrome, and it's going to affect my life, ...
Wolff-Parkinson-White syndrome stories
I HAD NO IDEA THAT I HAD WPW UNTIL I WOKE UP IN HOSPITAL AND WAS TOLD THAT I HAD IT . I HAD 2 MASSIVE HEART ATTACKS APPARENTLY DIED TWICE GOT PUT INTO A COMA WHILE I WAS IN THE COMA I WAS GIVEN A 10% CHANCE THAT I WOULD COME OUT OF IT. THEY SAID IF ...
Wolff-Parkinson-White syndrome stories
About 10 years ago, I was diagnosed with WPW. Had the surgery within a year to correct it, and have been symptom free ever since.
Wolff-Parkinson-White syndrome stories
when I was 18 days old I wasn't feeding very well so mummy took me to the doctors the next day at 19 days, we saw a locum doctor who said I had oral thrush which is why I wasn't feeding. On the day I turned 20 days old I started making a grunting noi...

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I went to the hospital yesterday for my review of ecg, heart scan and 24 hour monitor results as in March I was admitted to a&e for being dehydrated in pregnancy. Im currently 24 weeks pregnant with my first and have now been diagnosed with this ...

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