Amyloidosis synonyms

Amyloidosis is a rare and complex group of diseases characterized by the abnormal accumulation of amyloid proteins in various organs and tissues throughout the body. These proteins, which are usually produced in the bone marrow, can misfold and form insoluble fibrils that deposit in organs, disrupting their normal structure and function.

There are several synonyms or alternative names used to refer to amyloidosis:

• Primary Amyloidosis: Also known as AL amyloidosis, this form occurs when abnormal plasma cells in the bone marrow produce excessive amounts of amyloid proteins.


• Secondary Amyloidosis: Also called AA amyloidosis, this type is associated with chronic inflammatory diseases, such as rheumatoid arthritis or inflammatory bowel disease.


• Familial Amyloidosis: This form is inherited and caused by mutations in specific genes, leading to the production of abnormal amyloid proteins.


• Hereditary Amyloidosis: Similar to familial amyloidosis, this type is also inherited and caused by genetic mutations that affect the production of amyloid proteins.


• Systemic Amyloidosis: This term refers to amyloidosis that affects multiple organs and tissues throughout the body.


• Localized Amyloidosis: In contrast to systemic amyloidosis, this type is confined to a specific organ or tissue, such as the skin, lungs, or bladder.

It is important to note that amyloidosis can affect various organs, including the heart, kidneys, liver, spleen, nervous system, and gastrointestinal tract, among others. The symptoms and severity of the disease can vary depending on the organs involved and the extent of amyloid deposition.

Early diagnosis and appropriate management are crucial in amyloidosis to prevent further organ damage and improve patient outcomes. Treatment options may include chemotherapy, stem cell transplantation, targeted therapies, and supportive care to alleviate symptoms and manage complications.