Castleman disease is a rare disorder that affects the lymph nodes and related tissues in the body. It is not contagious, meaning it cannot be transmitted from one person to another through direct contact or exposure. Castleman disease is characterized by the abnormal growth of cells in the lymphatic system, leading to the enlargement of lymph nodes.
The exact cause of Castleman disease is still unknown, but it is believed to involve an overactive immune response. There are two main types of Castleman disease: unicentric and multicentric. Unicentric Castleman disease affects a single lymph node or a group of lymph nodes in one region of the body, while multicentric Castleman disease involves multiple lymph nodes and can affect various organs.
Although Castleman disease is not contagious, it can still have a significant impact on a person's health. Symptoms may include enlarged lymph nodes, fatigue, night sweats, fever, weight loss, and flu-like symptoms. Treatment options for Castleman disease depend on the type and severity of the condition, and may include surgery, radiation therapy, chemotherapy, or targeted drug therapy.
It is important for individuals with Castleman disease to work closely with their healthcare team to manage their symptoms and receive appropriate treatment. Ongoing research is being conducted to better understand the causes and develop more effective treatments for this rare disease.