How do I know if I have Castleman disease?

Castleman disease, also known as Castleman syndrome or angiofollicular lymph node hyperplasia, is a rare disorder that affects the lymph nodes and related tissues in the body. It is characterized by an abnormal overgrowth of cells in the lymphatic system, leading to the formation of enlarged lymph nodes.

Diagnosing Castleman disease can be challenging as its symptoms can vary widely depending on the subtype and location of the disease. However, there are some common signs and symptoms that may indicate the presence of Castleman disease:

• Enlarged lymph nodes: One of the primary indicators of Castleman disease is the presence of enlarged lymph nodes. These swollen lymph nodes can be felt as lumps under the skin in various parts of the body, such as the neck, groin, armpits, or chest.


• Flu-like symptoms: Castleman disease can cause flu-like symptoms, including fever, fatigue, night sweats, and general malaise. These symptoms may persist or recur over a prolonged period.


• Unintentional weight loss: Significant and unexplained weight loss can be a potential sign of Castleman disease. If you have been losing weight without trying, it is advisable to consult a healthcare professional.


• Weakness and fatigue: Castleman disease can lead to persistent weakness and fatigue, which may impact your daily activities and overall quality of life.


• Additional symptoms: Depending on the subtype of Castleman disease, other symptoms may include swollen spleen, difficulty breathing, skin rash, nerve pain, and gastrointestinal problems.

If you are experiencing any of these symptoms, it is important to consult a healthcare professional for a proper evaluation and diagnosis. Castleman disease can be challenging to diagnose due to its rarity and similarity to other conditions. Your doctor may perform various tests, including blood tests, imaging scans, and a lymph node biopsy, to confirm the presence of Castleman disease.

It is crucial to remember that only a qualified healthcare professional can provide an accurate diagnosis. If you suspect Castleman disease or have concerns about your health, seek medical attention promptly.

by Diseasemaps