Castleman disease is a rare and complex disorder that affects the lymph nodes and related tissues. It was first described by Dr. Benjamin Castleman in the 1950s. The prevalence of Castleman disease is relatively low, with an estimated incidence of 1 in 100,000 individuals. However, it is important to note that the prevalence may vary depending on the subtype of the disease.
Castleman disease can occur at any age, but it is most commonly diagnosed in individuals between the ages of 30 and 40. There are two main subtypes of Castleman disease: unicentric and multicentric. Unicentric Castleman disease is localized and typically presents as a single enlarged lymph node, while multicentric Castleman disease involves multiple lymph nodes and can affect various organs.
Although Castleman disease is considered rare, it is crucial to raise awareness about this condition to ensure early diagnosis and appropriate management. Further research and collaboration among healthcare professionals are necessary to better understand the prevalence, causes, and treatment options for Castleman disease.