Is Chronic Fatigue Syndrome / M.E. hereditary?

Here you can see if Chronic Fatigue Syndrome / M.E. can be hereditary. Do you have any genetic components? Does any member of your family have Chronic Fatigue Syndrome / M.E. or may be more predisposed to developing the condition?


Is Chronic Fatigue Syndrome / M.E. hereditary?


Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME), is a complex and debilitating condition characterized by extreme fatigue that cannot be explained by any underlying medical condition. While the exact cause of CFS/ME is still unknown, researchers have been investigating various factors that may contribute to its development, including genetic predisposition.


Genetic studies have suggested that there might be a hereditary component to CFS/ME. However, it is important to note that no specific gene or set of genes has been definitively identified as the cause of the condition. Instead, researchers believe that multiple genetic and environmental factors interact to increase the risk of developing CFS/ME.


Several studies have indicated that individuals with a family history of CFS/ME are more likely to develop the condition themselves. This suggests that there may be certain genetic variations that increase susceptibility to CFS/ME. However, it is crucial to understand that having a family member with CFS/ME does not guarantee that an individual will also develop the condition. It simply indicates an increased risk compared to the general population.


One study published in 2005 examined the prevalence of CFS/ME in families and found that the risk of developing the condition was higher in first-degree relatives (such as siblings or parents) of individuals with CFS/ME compared to the general population. Another study published in 2011 also reported a higher prevalence of CFS/ME in families, suggesting a potential genetic influence.


However, it is important to consider other factors that may contribute to the observed familial clustering of CFS/ME. Shared environmental factors, such as lifestyle habits or exposure to certain infections, could also play a role in the increased risk among family members.


Furthermore, the development of CFS/ME is likely to be influenced by a combination of genetic, environmental, and individual factors. For example, certain genetic variations may increase susceptibility to the condition, but the actual onset of CFS/ME may require additional triggers, such as viral infections, physical or emotional stress, or hormonal imbalances.


It is worth noting that CFS/ME is a complex condition, and research is still ongoing to unravel its underlying causes. The hereditary component of CFS/ME is not fully understood, and more studies are needed to identify specific genes or genetic variations associated with the condition.


In conclusion, while there is evidence to suggest a potential hereditary component to Chronic Fatigue Syndrome / Myalgic Encephalomyelitis, the exact genetic factors involved and their contribution to the development of the condition are still unclear. It is likely that a combination of genetic, environmental, and individual factors play a role in the onset of CFS/ME. If you have concerns about the hereditary aspect of CFS/ME, it is recommended to consult with a healthcare professional or genetic counselor who can provide personalized information and guidance.


by Diseasemaps

Big question mark!!!!!

12/20/19 by ME International

I don't know. Even if my dad says my grandad was often in bed and was very very "lazy"...

8/27/17 by Emy 2050

Connective tissue disorder - which causes extreme fatigue and other health issues - is hereditary. Read about Elvis and his grandmother and their preference for lying down here: http://invisibleillnessforum.com/index.php?topic=39.0 The description "lazy" reminded me of Elvis's mother: Gladys's sister Lillian Reported Gladys to always be "lazy as a hog" And shirking her housework but she could rise to the occasion'.

8/29/17 by C.L. 100

There's no evidence for this.

9/5/17 by Shirley 2050

Open Medicine Foundation research is at the genetic level so if it is inherited they will probably find out first (www.omf.ngo).

9/7/17 by 2560

It's not known for sure but generally thought not to be

9/8/17 by Sam 1400

I do not know. I have not yet been tested for the genetic components that may contribute to the disease.

9/10/17 by Sharon 1500

It can be yes Some family members have got it at same time Apart from that i do not have the answers or knowledge

1/17/18 by Annette 2500

I have heard of families where more than one person has it. It is not that common but it does happen. Otherwise I do not have the answers.

3/2/18 by Beti 2700

Possibly. Look for patterns in your own family.

8/9/18 by cathy 2500

it is not hereditary but every disease has a group that is more prone to it it is not a women's disease the pediatric cases are about 50/50 male to female somehow the males fall off the roles after early 20s not sure how or why this happens

4/6/19 by Fadra 2550

CFS/ME is caused by chemical pollution in our air, soil, water, food, built environment, and consumer products. Genetics plays maybe a 5% role.

12/12/19 by Joanna 6200

That is a big question mark??? Many in the same family do have ME.

12/21/19 by Pam 3550

There is a genetic component, but it is not 100% hereditary. You often see people having multiple cases in one family (often mother and daughter), but there are a lot more cases where that isn't the case. There is currently a big genetic study ongoing in the UK that hopefully will provide some more answers.

11/18/22 by Arlette 1300
Translated from spanish Improve translation

No, although the answer is not known.

9/11/17 by Eduardo Casasnovas. Translated
Translated from spanish Improve translation

I'm not sure, it may be,neurons.

9/11/17 by Haydee de bielik. Translated
Translated from spanish Improve translation

As I said in the last question, I think that MS can be genetic. I have heard of cases of relatives that suffer from the same condition. There are abnormalities in the mitochondria.

10/19/17 by Heidrun Kroner. Translated

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