Cutis marmorata telangiectatica congenita (CMTC) is a rare vascular disorder characterized by localized or generalized persistent cutis marmorata, which refers to a mottled or marbled appearance of the skin due to dilated blood vessels. The exact prevalence of CMTC is not well-established, as it is a relatively uncommon condition. However, it is estimated to occur in approximately 1 in 2,500 to 1 in 50,000 live births.
CMTC is typically present at birth or appears within the first few weeks of life. It can affect both males and females, and there is no known ethnic or geographic predilection. The condition may vary in severity, with some individuals experiencing mild symptoms while others have more extensive involvement.
While the exact cause of CMTC is unknown, it is believed to result from abnormalities in the development of blood vessels during fetal development. The condition is usually sporadic, meaning it occurs randomly without a family history. However, in rare cases, CMTC may be inherited in an autosomal dominant or recessive manner.
Early recognition and appropriate management of CMTC are crucial to address potential complications and provide supportive care. The treatment primarily focuses on symptom management and may involve measures such as protecting the skin from temperature extremes and providing regular follow-up with healthcare professionals.